Health Topics
A muscle disorder causes patterns of weakness, loss of muscle tissue, electromyogram (EMG) findings, or biopsy results that suggest a muscle problem. The muscle disorder can be inherited, such as muscular dystrophy, or acquired, such as alcoholic or steroid myopathy.
The medical name for muscle disorder is myopathy.
Symptoms
The main symptom is weakness.
Other symptoms include cramps and stiffness.
Exams and Tests
Your health care provider will take your medical history and perform a neurological exam. Tests that may be ordered include:
- Blood and urine tests
- Electromyography (EMG) and nerve conduction studies (NCS)
- Muscle biopsy
- Genetic tests to look for conditions that run in families. This can be tested with blood tests or sometimes saliva testing.
A muscle biopsy examines a tissue sample under a microscope to confirm disease. Sometimes, a blood or saliva test to check for a genetic condition is all that is needed based on someone's symptoms and family history.
Treatment
Treatment depends on the cause. It usually includes:
- Bracing
- Medicines (such as corticosteroids in some cases)
- Dietary changes
- Enzyme replacement therapy
- Gene replacement therapy
- Physical, respiratory, and occupational therapies
- Preventing the condition from getting worse by treating the underlying condition causing the muscle weakness
- Surgery (sometimes)
Your provider can tell you more about your condition and treatment options.
Alternative Names
Myopathic changes; Myopathy; Muscle problem
Images
References
Borg K. Myopathies. In: Frontera WR, Silver JK, eds. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 5th ed. Philadelphia, PA: Elsevier; 2026:chap 133.
Doughty CT, Amato AA. Disorders of skeletal muscle. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 109.
Selcen D. Muscle diseases. In: Goldman L, Cooney K, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 389.
Review Date 10/27/2025
Updated by: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

