These ingredients in Contac can be harmful in large amounts:

• Acetaminophen (Tylenol)
• Chlorpheniramine
• Phenylpropanolamine
• Dextromethorphan hydrobromide
• Diphenhydramine hydrochloride
• Pseudoephedrine hydrochloride

Note: Not all of these ingredients are found in every form of Contac.

Besides being in Contac, these ingredients are also found in some over-the-counter herbal products advertised to help with weight loss and athletic performance.

Symptoms of a Contac overdose include:

• Agitation
• Blurred vision
• Convulsions (seizures)
• Depression
• Delirium (acute confusion)
• Disorientation, nervousness, hallucinations
• Drowsiness
• Enlarged (dilated) pupils
• Fever
• Inability to urinate or completely empty the bladder
• Increased blood pressure
• Irregular heartbeat
• Muscle pain and spasms, tremor, unsteadiness
• Nausea and vomiting
• Rapid heartbeat
• Yellow eyes due to jaundice

Have this information ready:

• The person's age, weight, and condition
• Name of the product (ingredients and strength, if known)
• Time it was swallowed
• Amount swallowed
• If the medicine was prescribed for the person

Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

Take the container with you to the hospital, if possible.

Your health care provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.

Tests that may be done include:

• Blood and urine tests
• Chest x-ray
• CT scan (advanced imaging) of the brain for neurologic symptoms
• Electrocardiogram (ECG) or heart tracing

Treatment may include:

• Activated charcoal
• Fluids through a vein (IV)
• Medicine to treat symptoms
• Laxative
• Breathing support, including oxygen, tube through the mouth into the lungs, and breathing machine (ventilator)

This type of overdose tends to be mild. However, if the person swallowed enough of the product, serious complications (such as liver damage) can occur. This is from the acetaminophen in the product. How well a person does depends on how much was taken and how soon they receive treatment. Serious heart rhythm disturbances and death can occur.

Aronson JK. Ephedra, ephedrine, and pseudoephedrine. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:65-75.

Ganetsky M. Acetaminophen. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 138.

Updated by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.