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• Summary
• Start Here
• Symptoms
• Diagnosis and Tests

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• Related Issues
• Specifics
• Genetics

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Research

• Clinical Trials
• Journal Articles

Resources

• Reference Desk
• Find an Expert

For You

• Children
• Patient Handouts

Summary

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Blood disorders affect one or more parts of the blood and prevent your blood from doing its job. They can be acute or chronic. Many blood disorders are inherited. Other causes include other diseases, side effects of medicines, and a lack of certain nutrients in your diet.

Types of blood disorders include:

• Platelet disorders, excessive clotting, and bleeding problems, which affect how your blood clots
• Anemia, which happens when your blood does not carry enough oxygen to the rest of your body
• Cancers of the blood, such as leukemia and myeloma
• Eosinophilic disorders, which are problems with one type of white blood cell.

Start Here

• Blood (For Parents) (Nemours Foundation) Also in Spanish
• Blood Diseases (National Institute of Diabetes and Digestive and Kidney Diseases) Also in Spanish

Symptoms

• Symptoms of Blood Disorders (Merck & Co., Inc.) Also in Spanish

Diagnosis and Tests

• Blood Count Tests: MedlinePlus Health Topic (National Library of Medicine) Also in Spanish
• Blood Tests (National Heart, Lung, and Blood Institute) Also in Spanish
• Haptoglobin (HP) Test (National Library of Medicine) Also in Spanish
• Hemoglobin Electrophoresis (National Library of Medicine) Also in Spanish
• Karyotype Genetic Test (National Library of Medicine) Also in Spanish

Related Issues

• Lupus and the Heart, Lungs, and Blood (Lupus Foundation of America) Also in Spanish

Specifics

• Eosinophilia (Mayo Foundation for Medical Education and Research) Also in Spanish
• Heavy Chain Diseases (Merck & Co., Inc.) Also in Spanish
• Hemoglobin C, S-C, and E Diseases (Merck & Co., Inc.) Also in Spanish
• High Red Blood Cell Count (Mayo Foundation for Medical Education and Research) Also in Spanish
• Low White Blood Cell Count (Mayo Foundation for Medical Education and Research) Also in Spanish
• Lymphocytosis (High Lymphocyte Count) (Mayo Foundation for Medical Education and Research) Also in Spanish
• Monoclonal Gammopathies (Johns Hopkins Medicine)
• Neutropenia (Low Neutrophil Count) (Mayo Foundation for Medical Education and Research) Also in Spanish
• Overview of Plasma Cell Disorders (Merck & Co., Inc.) Also in Spanish
• Overview of White Blood Cell Disorders (Merck & Co., Inc.) Also in Spanish
• Paroxysmal Nocturnal Hemoglobinuria (PNH) (Aplastic Anemia and MDS International Foundation)
• Polycythemia Vera (Mayo Foundation for Medical Education and Research)
• What Is Lymphopenia? (National Heart, Lung, and Blood Institute)

Genetics

• Aceruloplasminemia: MedlinePlus Genetics (National Library of Medicine)
• CLPB deficiency: MedlinePlus Genetics (National Library of Medicine)
• Congenital plasminogen deficiency: MedlinePlus Genetics (National Library of Medicine)
• Dyserythropoietic anemia and thrombocytopenia: MedlinePlus Genetics (National Library of Medicine)
• Familial erythrocytosis: MedlinePlus Genetics (National Library of Medicine)
• Hereditary spherocytosis: MedlinePlus Genetics (National Library of Medicine)
• McLeod neuroacanthocytosis syndrome: MedlinePlus Genetics (National Library of Medicine)
• Methemoglobinemia, beta-globin type: MedlinePlus Genetics (National Library of Medicine)
• Neuroferritinopathy: MedlinePlus Genetics (National Library of Medicine)
• Paroxysmal nocturnal hemoglobinuria: MedlinePlus Genetics (National Library of Medicine)
• Polycythemia vera: MedlinePlus Genetics (National Library of Medicine)
• X-linked sideroblastic anemia: MedlinePlus Genetics (National Library of Medicine)

Clinical Trials

• ClinicalTrials.gov: Blood Cells (National Institutes of Health)
• ClinicalTrials.gov: Hematologic Diseases (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

• Article: Quantitative detection of macular microvascular abnormalities identified by optical coherence tomography...
• Article: When Chinese patients with plasma cell disorders encountered the nationwide Omicron...
• Article: Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in hematological diseases.
• Blood Disorders -- see more articles

Reference Desk

• Hematology Glossary (American Society of Hematology)

Find an Expert

• Find a Hematologist (American Society of Hematology)
• National Heart, Lung, and Blood Institute

Children

• Hereditary Spherocytosis (Nemours Foundation) Also in Spanish

Patient Handouts

• Blood differential test (Medical Encyclopedia) Also in Spanish
• Blood smear (Medical Encyclopedia) Also in Spanish
• CBC blood test (Medical Encyclopedia) Also in Spanish
• Hematocrit (Medical Encyclopedia) Also in Spanish
• Hemoglobin (Medical Encyclopedia) Also in Spanish
• Low white blood cell count and cancer (Medical Encyclopedia) Also in Spanish
• RBC count (Medical Encyclopedia) Also in Spanish
• RBC indices (Medical Encyclopedia) Also in Spanish
• WBC count (Medical Encyclopedia) Also in Spanish