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Cystic Fibrosis
URL of this page: https://medlineplus.gov/cysticfibrosis.html

Cystic Fibrosis

Also called: CF
On this page

Basics

  • Summary
  • Start Here
  • Diagnosis and Tests
  • Prevention and Risk Factors
  • Treatments and Therapies

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  • Living With
  • Related Issues
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  • Journal Articles

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Summary

Cystic fibrosis (CF) is an inherited disease of the mucus and sweat glands. It affects mostly your lungs, pancreas, liver, intestines, sinuses, and sex organs. CF causes your mucus to be thick and sticky. The mucus clogs the lungs, causing breathing problems and making it easy for bacteria to grow. This can lead to repeated lung infections and lung damage.

The symptoms and severity of CF can vary. Some people have serious problems from birth. Others have a milder version of the disease that doesn't show up until they are teens or young adults. Sometimes you will have few symptoms, but later you may have more symptoms.

CF is diagnosed through various tests, such as gene, blood, and sweat tests. There is no cure for CF, but treatments have improved greatly in recent years. In the past, most deaths from CF were in children and teenagers. Today, with improved treatments, some people who have CF are living into their forties, fifties, or older. Treatments may include chest physical therapy, nutritional and respiratory therapies, medicines, and exercise.

NIH: National Heart, Lung, and Blood Institute

Start Here

  • About Cystic Fibrosis (Cystic Fibrosis Foundation)
  • Cystic Fibrosis (American Lung Association)
  • What Is Cystic Fibrosis? From the National Institutes of Health (National Heart, Lung, and Blood Institute)

Diagnosis and Tests

  • Chymotrypsin in Stool From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Cystic Fibrosis (CF) Respiratory Screen: Sputum (Nemours Foundation) Also in Spanish
  • Cystic Fibrosis: Prenatal Screening and Diagnosis (American College of Obstetricians and Gynecologists)
  • Stool Elastase From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Sweat Test for Cystic Fibrosis From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Testing for CF (Cystic Fibrosis Foundation)

Prevention and Risk Factors

  • Cystic Fibrosis and Pregnancy (March of Dimes Foundation) Also in Spanish

Treatments and Therapies

  • Drug Development Pipeline (Cystic Fibrosis Foundation)
  • Managing Cystic Fibrosis (CF) (Cystic Fibrosis Foundation)

Living With

  • Airway Clearance Techniques (ACTs) Video (Cystic Fibrosis Foundation)
  • Chest Physical Therapy (Cystic Fibrosis Foundation)
  • Consider Tube Feeding (Cystic Fibrosis Foundation)
  • Day-to-Day Exercise and Cystic Fibrosis (CF) (Cystic Fibrosis Foundation) - PDF
  • Dietary Tips for Kids With Cystic Fibrosis (Nemours Foundation) Also in Spanish
  • Pulmonary Rehabilitation: MedlinePlus Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish

Related Issues

  • A Teacher's Guide to Cystic Fibrosis (Cystic Fibrosis Foundation)
  • Accommodations for College (Cystic Fibrosis Foundation)
  • Aspergillus and Allergic Bronchopulmonary Aspergillosis Video (Cystic Fibrosis Foundation)
  • COVID-19 Community Questions and Answers (Cystic Fibrosis Foundation)
  • Cystic Fibrosis-Related Diabetes (Cystic Fibrosis Foundation)
  • Infections and Cystic Fibrosis (Cystic Fibrosis Foundation)
  • Marvels of Mucus and Phlegm: The Slime That Keeps You Healthy From the National Institutes of Health (National Institutes of Health) Also in Spanish
  • Methicillin-Resistant Staphylococcus aureus (MRSA) (Cystic Fibrosis Foundation)

Genetics

  • Cystic fibrosis: MedlinePlus Genetics From the National Institutes of Health (National Library of Medicine)
  • Learning about Cystic Fibrosis From the National Institutes of Health (National Human Genome Research Institute)

Clinical Trials

  • ClinicalTrials.gov: Cystic Fibrosis From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: Effects of Oral Amino Acid Supplementation on Physical Activity, Systemic Inflammation,...
  • Article: Forced expiration technique: impact on the respiratory mechanics parameters of children...
  • Article: Implementation of Cystic Fibrosis Responsibility, Independence, Self-Care, Education Program Enhances Cystic...
  • Cystic Fibrosis -- see more articles

Find an Expert

  • Cystic Fibrosis Foundation
  • National Heart, Lung, and Blood Institute From the National Institutes of Health
  • National Institute of Diabetes and Digestive and Kidney Diseases From the National Institutes of Health

Teenagers

  • Dietary Tips for Teens with Cystic Fibrosis (Nemours Foundation) Also in Spanish

Patient Handouts

  • Cystic fibrosis (Medical Encyclopedia) Also in Spanish
  • Cystic fibrosis - nutrition (Medical Encyclopedia) Also in Spanish
  • How to breathe when you are short of breath (Medical Encyclopedia) Also in Spanish
  • Neonatal cystic fibrosis screening test (Medical Encyclopedia) Also in Spanish
  • Postural drainage (Medical Encyclopedia) Also in Spanish
  • Sweat electrolytes test (Medical Encyclopedia) Also in Spanish

Topic Image

Cystic Fibrosis

MEDICAL ENCYCLOPEDIA

  • Cystic fibrosis
  • Cystic fibrosis - nutrition
  • Fecal fat
  • How to breathe when you are short of breath
  • Neonatal cystic fibrosis screening test
  • Oxygen safety
  • Postural drainage
  • Secretin stimulation test
  • Sweat electrolytes test
  • Traveling with breathing problems
  • Trypsin and chymotrypsin in stool
  • Trypsinogen test
  • Using oxygen at home
  • Using oxygen at home - what to ask your doctor

Related Health Topics

  • Lung Transplantation
  • Oxygen Therapy
  • Pulmonary Rehabilitation

National Institutes of Health

The primary NIH organization for research on Cystic Fibrosis is the National Heart, Lung, and Blood Institute

Disclaimers

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The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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