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Diabetes Insipidus
URL of this page: https://medlineplus.gov/diabetesinsipidus.html

Diabetes Insipidus

Also called: DI
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Summary

Diabetes insipidus (DI) causes frequent urination. You become extremely thirsty, so you drink. Then you urinate. This cycle can keep you from sleeping or even make you wet the bed. Your body produces lots of urine that is almost all water.

DI is different from diabetes mellitus (DM), which involves insulin problems and high blood sugar. The symptoms can be similar. However, DI is related to how your kidneys handle fluids. It's much less common than DM. Urine and blood tests can show which one you have.

Usually, DI is caused by a problem with your pituitary gland or your kidneys. Treatment depends on the cause of the problem. Medicines can often help.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Start Here

  • Diabetes Insipidus (Endocrine Society)
  • Diabetes Insipidus From the National Institutes of Health (National Institute of Diabetes and Digestive and Kidney Diseases)

Diagnosis and Tests

  • Osmolality Tests From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Sodium Blood Test From the National Institutes of Health (National Library of Medicine) Also in Spanish

Genetics

  • Nephrogenic diabetes insipidus: MedlinePlus Genetics From the National Institutes of Health (National Library of Medicine)
  • Neurohypophyseal diabetes insipidus: MedlinePlus Genetics From the National Institutes of Health (National Library of Medicine)
  • Wolfram syndrome: MedlinePlus Genetics From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • ClinicalTrials.gov: Diabetes Insipidus From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: Development and validation of a predictive machine learning model for postoperative...
  • Article: Urinary oxytocin secretion after pituitary surgery, early arginine vasopressin deficiency and...
  • Article: Nomogram for predicting diabetes insipidus following endoscopic transsphenoidal surgery in pituitary...
  • Diabetes Insipidus -- see more articles

Find an Expert

  • National Institute of Diabetes and Digestive and Kidney Diseases From the National Institutes of Health

Patient Handouts

  • Central diabetes insipidus (Medical Encyclopedia) Also in Spanish
  • Diabetes insipidus (Medical Encyclopedia) Also in Spanish
  • Nephrogenic diabetes insipidus (Medical Encyclopedia) Also in Spanish

Topic Image

Diabetes Insipidus

MEDICAL ENCYCLOPEDIA

  • Antidiuretic hormone blood test
  • Central diabetes insipidus
  • Diabetes insipidus
  • Nephrogenic diabetes insipidus
  • Thirst - excessive
  • Urine 24-hour volume
  • Urine concentration test

Related Health Topics

  • Pituitary Disorders

National Institutes of Health

The primary NIH organization for research on Diabetes Insipidus is the National Institute of Diabetes and Digestive and Kidney Diseases

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The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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