The cause of esophageal spasm is unknown. Very hot or very cold foods may trigger spasms in some people. Muscle or nerve problems in the esophagus may cause the spasm.

Symptoms may include:

• Problems swallowing or pain with swallowing
• Pain in the chest or upper abdomen

It can be hard to tell a spasm from angina pectoris, a symptom of heart disease. The pain may spread to the neck, jaw, arms, or back

Tests you may need to look for the condition include:

• Esophagogastroduodenoscopy (EGD)
• Esophageal manometry
• Esophagogram (barium swallow x-ray)
• Heart evaluation if there is concern that the spasm sensation stems from heart disease
  

Nitroglycerin given under the tongue (sublingual) may help a sudden episode of esophageal spasm. Long-acting nitroglycerin and calcium channel blockers are also used for the problem.

Long-term (chronic) cases are sometimes treated with low-dose antidepressants such as trazodone or nortriptyline to reduce symptoms.

Occasionally, spasm may improve with medicines that block acid production.

Botulinum toxin injections may be done into the esophagus for some conditions that may cause esophageal spasm, such as achalasia, and for distal esophageal spasm.

Rarely, certain cases may need dilation (widening) of the esophagus by endoscopic myotomy (cutting the affected muscles in the esophagus). Surgery may be needed to control symptoms in the case of spastic achalasia.

An esophageal spasm may come and go (intermittent) or last for a long time (chronic). Medicine can help relieve symptoms in many cases. However, other treatments may be needed, especially in the case of achalasia.

The condition may not respond to treatment.

Contact your health care provider if you have symptoms of esophageal spasm that don't go away. The symptoms may actually be due to heart problems. Your provider can help decide if you need heart tests.

Avoid very hot or very cold foods if you get esophageal spasms. If the spasm also causes trouble swallowing, avoiding difficult foods such as meat, dry breads, and rice may help.

Spasm of the esophagus; Distal esophageal spasm; Jackhammer esophagus; Achalasia

Falk GW, Katzka DA. Diseases of the esophagus. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 124.

Pandolfino JE, Kahrilas PJ. Esophageal neuromuscular function and motility disorders. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 44.

Updated by: Jenifer K. Lehrer, MD, Gastroenterologist, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.