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Orbital pseudotumor is the swelling of tissue behind the eye in an area called the orbit. The orbit is the hollow space in the skull where the eye sits. The orbit protects the eyeball and the muscles and tissue that surround it. Orbital pseudotumor does not spread to other tissues or places in the body.
Causes
The cause is unknown. It mostly affects young women, although it can occur at any age.
Symptoms
Symptoms may include:
- Pain in eye, and it may be severe
- Restricted eye movement
- Decreased vision
- Double vision
- Eye swelling (proptosis)
- Red eye (rare)
Exams and Tests
The health care provider will examine your eye. If you have signs of pseudotumor, additional tests will be done to make sure you don't have other conditions that may look like pseudotumor. The two most common other conditions are:
- A cancerous tumor in the orbit
- Thyroid eye disease
Tests may include:
- CT scan of the head
- MRI of the head
- Ultrasound of the head
- Skull x-ray
- Biopsy
Treatment
Mild cases may go away without treatment. More severe cases most often respond well to corticosteroid treatment. If the condition is very bad, the swelling may put pressure on the eyeball and damage it. Surgery may be needed to remove part of the bones of the orbit to relieve the pressure.
Outlook (Prognosis)
Most cases are mild and outcomes are good. Severe cases may not respond well to treatment and there may be some loss of vision. Orbital pseudotumor most often involves only one eye.
Possible Complications
Severe cases of orbital pseudotumor may push the eye forward so much that the lids cannot cover and protect the cornea. This causes the eye to dry out. The cornea may become cloudy or develop an ulcer. Also, the eye muscles may not be able to properly aim the eye which can cause double vision.
When to Contact a Medical Professional
People with this condition need regular follow-up care with an eye doctor who is familiar with the treatment of orbital disease.
Contact your provider right away if you have any of the following problems:
- Irritation of the cornea
- Redness
- Pain
- Decreased vision
Alternative Names
Idiopathic orbital inflammatory syndrome (IOIS); Non-specific orbital inflammation
Images
References
Cioffi GA, Liebmann JM. Diseases of the visual system. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 395.
McNab AA. Orbital infection and inflammation. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 12.14.
Wang MY, Rubin RM, Sadun AA. Ocular myopathies. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 9.18.
Yucel Gencoglu A, Mangan MS. Orbital inflammatory pseudotumor following mRNA COVID-19 vaccination. Ocul Immunol Inflamm. Aug 2022:1-4. PMID: 35914301 pubmed.ncbi.nlm.nih.gov/35914301/.
Review Date 8/22/2022
Updated by: Franklin W. Lusby, MD, Ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.