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How Genes Work →
What are proteins and what do they do?
URL of this page: https://medlineplus.gov/genetics/understanding/howgeneswork/protein/

What are proteins and what do they do?

Proteins are large, complex molecules that play many critical roles in the body. They do most of the work in cells and are required for the structure, function, and regulation of the body’s tissues and organs.

Proteins are made up of hundreds or thousands of smaller units called amino acids, which are attached to one another in long chains. There are 20 different types of amino acids that can be combined to make a protein. The sequence of amino acids determines each protein’s unique 3-dimensional structure and its specific function. Amino acids are coded by combinations of three DNA building blocks (nucleotides), determined by the sequence of genes.

Proteins can be described according to their large range of functions in the body, listed in alphabetical order:

Examples of protein functions

Function

Description

Example

Antibody

Antibodies bind to specific foreign particles, such as viruses and bacteria, to help protect the body.

Immunoglobulin G (IgG)

Enzyme

Enzymes carry out almost all of the thousands of chemical reactions that take place in cells. They also assist with the formation of new molecules by reading the genetic information stored in DNA.

Phenylalanine hydroxylase

Messenger

Messenger proteins, such as some types of hormones, transmit signals to coordinate biological processes between different cells, tissues, and organs.

Growth hormone

Structural component

These proteins provide structure and support for cells. On a larger scale, they also allow the body to move.

Actin

Transport/storage

These proteins bind and carry atoms and small molecules within cells and throughout the body.

Ferritin

For more information about proteins and their functions:

The National Human Genome Research Institute (NHGRI) Talking Glossary of Genomic and Genetic Terms has information about proteins and amino acids.From the National Institutes of Health

Arizona State University's "Ask a Biologist" discusses different kinds of proteins.

Topics in the How Genes Work chapter

  • What are proteins and what do they do?
  • How do genes direct the production of proteins?
  • Can genes be turned on and off in cells?
  • What is epigenetics?
  • How do cells divide?
  • How do genes control the growth and division of cells?
  • How do geneticists indicate the location of a gene?

Other chapters in Help Me Understand Genetics

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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