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Plague
URL of this page: https://medlineplus.gov/plague.html

Plague

Also called: Bubonic plague, Pneumonic plague
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Summary

Plague is an infection caused by the bacterium Yersinia pestis. The bacteria are found mainly in rats and in the fleas that feed on them. People and other animals can get plague from rat or flea bites. In the past, plague destroyed entire civilizations. Today plague is uncommon, due to better living conditions and antibiotics.

There are three forms of plague:

  • Bubonic plague causes the tonsils, adenoids, spleen, and thymus to become inflamed. Symptoms include fever, aches, chills, and tender lymph glands.
  • In septicemic plague, bacteria multiply in the blood. It causes fever, chills, shock, and bleeding under the skin or other organs.
  • Pneumonic plague is the most serious form. Bacteria enter the lungs and cause pneumonia. People with the infection can spread this form to others. This type could be a bioterror agent.

Lab tests can diagnose plague. Treatment is a strong antibiotic. There is no vaccine.

Start Here

  • About Plague (Centers for Disease Control and Prevention)
  • How Plague Spreads (Centers for Disease Control and Prevention)
  • Plague From the National Institutes of Health (National Institute of Allergy and Infectious Diseases)
  • Plague Factsheet (Department of the Interior) - PDF

Symptoms

  • Signs and Symptoms of Plague (Centers for Disease Control and Prevention)

Diagnosis and Tests

  • Diagnosing Plague (Centers for Disease Control and Prevention)

Prevention and Risk Factors

  • Preventing Plague (Centers for Disease Control and Prevention) - PDF

Statistics and Research

  • Plague: Maps and Statistics (Centers for Disease Control and Prevention)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: Unraveling the role of rat and flea population dynamics on the...
  • Article: Assessing the impacts of climate anomalies on plague risk in China...
  • Article: The interplay between species and locations shapes vector fleas microbial communities...
  • Plague -- see more articles

Find an Expert

  • Centers for Disease Control and Prevention Also in Spanish
  • National Institute of Allergy and Infectious Diseases From the National Institutes of Health
  • World Health Organization

Patient Handouts

  • Plague (Medical Encyclopedia) Also in Spanish

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Plague

MEDICAL ENCYCLOPEDIA

  • Plague

Related Health Topics

  • Biodefense and Bioterrorism

National Institutes of Health

The primary NIH organization for research on Plague is the National Institute of Allergy and Infectious Diseases

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