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Basics
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Summary
Tuberous sclerosis is a rare genetic disease that causes benign tumors to grow in the brain and other organs. Symptoms vary, depending on where the tumors grow. They could include:
- Skin problems, such as light patches and thickened skin
- Seizures
- Behavior problems
- Intellectual disabilities
- Kidney problems
Some people have signs of tuberous sclerosis at birth. In others it can take time for the symptoms to develop. The disease can be mild, or it can cause severe disabilities. In rare cases, tumors in vital organs or other symptoms can be life-threatening.
Tuberous sclerosis has no cure, but treatments can help symptoms. Options include medicines, educational and occupational therapy, surgery, or surgery to treat specific complications.
NIH: National Institute of Neurological Disorders and Stroke
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Tuberous Sclerosis Complex
(National Institute of Neurological Disorders and Stroke)
Genetics
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Tuberous sclerosis complex: MedlinePlus Genetics
(National Library of Medicine)
Clinical Trials
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ClinicalTrials.gov: Tuberous Sclerosis
(National Institutes of Health)
Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)
Find an Expert
Children
- Tuberous Sclerosis Complex (For Parents) (Nemours Foundation) Also in Spanish
Patient Handouts
- Tuberous sclerosis (Medical Encyclopedia) Also in Spanish
The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.