Health Topics

Skip navigation

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( Lock Locked padlock icon ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

You Are Here:
Home →
Tay-Sachs Disease
URL of this page: https://medlineplus.gov/taysachsdisease.html

Tay-Sachs Disease

On this page

Basics

Learn More

See, Play and Learn

  • No links available

Research

Resources

For You

Summary

Tay-Sachs disease is a rare, inherited disease. It is a type of lipid metabolism disorder. It causes too much of a fatty substance to build up in the brain. This buildup destroys nerve cells, causing mental and physical problems.

Infants with Tay-Sachs disease appear to develop normally for the first few months of life. Then mental and physical abilities decline. The child becomes blind, deaf, and unable to swallow. Muscles begin to waste away and paralysis sets in. Even with the best of care, children with Tay-Sachs disease usually die by age 4.

The cause is a gene mutation which is most common in Eastern European Ashkenazi Jews. To get the disease, both parents must have the gene. If they do, there is a 25% chance of the child having the disease. A blood test and prenatal tests can check for the gene or the disease.

There is no cure. Medicines and good nutrition can help some symptoms. Some children need feeding tubes.

NIH: National Institute of Neurological Disorders and Stroke

Start Here

Diagnosis and Tests

Prevention and Risk Factors

Related Issues

Genetics

Clinical Trials

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

Patient Handouts

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.