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VLDL Cholesterol
URL of this page: https://medlineplus.gov/vldlcholesterol.html

VLDL Cholesterol

Summary

What is cholesterol?

Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Your liver makes cholesterol, and it is also in some foods, such as meat and dairy products. Your body needs some cholesterol to work properly. But having too much cholesterol in your blood raises your risk of coronary artery disease.

What is VLDL cholesterol?

VLDL stands for very-low-density lipoprotein. Your liver makes VLDL and releases it into your bloodstream. The VLDL particles mainly carry triglycerides, another type of fat, to your tissues. VLDL is similar to LDL cholesterol, but LDL mainly carries cholesterol to your tissues instead of triglycerides.

VLDL and LDL are sometimes called "bad" cholesterols because they can contribute to the buildup of plaque in your arteries. This buildup is called atherosclerosis. The plaque that builds up is a sticky substance made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, the plaque hardens and narrows your arteries. This limits the flow of oxygen-rich blood to your body. It can lead to coronary artery disease and other heart diseases.

How do I know what my VLDL level is?

There isn't a way to directly measure your VLDL level. Instead, you will most likely get a blood test to measure your triglyceride level. The lab can use your triglyceride level to estimate what your VLDL level is. Your VLDL is about one-fifth of your triglyceride level. However, estimating your VLDL this way does not work if your triglyceride level is very high.

What should my VLDL level be?

Your VLDL level should be less than 30 mg/dL (milligrams per deciliter). Anything higher than that puts you at risk of heart disease and stroke.

How can I lower my VLDL level?

Because VLDL and triglycerides are linked, you can lower your VLDL level by lowering your triglyceride level. You may be able to lower your triglycerides with a combination of losing weight, changing your diet, and getting exercise. It is important to switch to healthy fats and cut back on sugar and alcohol. Some people may also need to take medicines.

Learn More

  • Apolipoprotein CII (Medical Encyclopedia) Also in Spanish
  • Cholesterol Levels From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Cholesterol Levels: What You Need to Know: MedlinePlus Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Dietary fats explained (Medical Encyclopedia) Also in Spanish
  • How to Lower Cholesterol: MedlinePlus Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Triglyceride level (Medical Encyclopedia) Also in Spanish
  • VLDL Cholesterol: Is It Harmful? (Mayo Foundation for Medical Education and Research) Also in Spanish
  • VLDL test (Medical Encyclopedia) Also in Spanish

Genetics

  • Hepatic lipase deficiency: MedlinePlus Genetics From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • ClinicalTrials.gov: VLDL Cholesterol From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: Refining the Martin-Hopkins method for estimating low-density lipoprotein cholesterol levels: Median...
  • Article: Distinct lipoprotein contributions to valvular heart disease: Insights from genetic analysis.
  • Article: VLDL triglycerides and cholesterol in non-alcoholic fatty liver disease and myocardial...
  • VLDL Cholesterol -- see more articles

Patient Handouts

  • VLDL test (Medical Encyclopedia) Also in Spanish

Topic Image

VLDL Cholesterol

Related Health Topics

  • Cholesterol
  • Cholesterol Medicines
  • Dietary Fats
  • HDL: The "Good" Cholesterol
  • LDL: The "Bad" Cholesterol
  • Triglycerides

National Institutes of Health

The primary NIH organization for research on VLDL Cholesterol is the National Heart, Lung, and Blood Institute

Disclaimers

MedlinePlus links to health information from the National Institutes of Health and other federal government agencies. MedlinePlus also links to health information from non-government Web sites. See our disclaimer about external links and our quality guidelines.

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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