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Hodgkin Lymphoma
URL of this page: https://medlineplus.gov/hodgkinlymphoma.html

Hodgkin Lymphoma

Also called: Hodgkin Disease
On this page

Basics

  • Summary
  • Start Here
  • Diagnosis and Tests
  • Prevention and Risk Factors
  • Treatments and Therapies

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  • Related Issues

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Summary

What is Hodgkin lymphoma?

Hodgkin lymphoma, also called Hodgkin disease, is a type of cancer that develops in the lymph system. Your lymph system is part of your immune system. It helps protect your body from infection and disease.

The lymph system is made up of tissues and organs that produce, store, and carry white blood cells. It includes your:

  • Bone marrow
  • Lymph nodes
  • Lymphatic vessels
  • Spleen
  • Thymus
  • Tonsils

Hodgkin lymphoma is one of the main types of lymphoma. The other is non-Hodgkin lymphoma. Each type starts in different types of white blood cells.

What causes Hodgkin lymphoma?

The cause of Hodgkin lymphoma is unknown. But there are certain people who are at higher risk of developing it.

Who is more likely to develop Hodgkin lymphoma?

Certain factors can make you more likely to develop Hodgkin lymphoma:

  • Age. Hodgkin lymphoma is most common in early adulthood (age 20-39 years) and in late adulthood (age 65 years and older).
  • Being male. The risk of adult Hodgkin lymphoma is slightly higher in males than in females.
  • Past Epstein-Barr virus (EBV) infection. Having an infection with EBV as a young child or teenager increases your risk of Hodgkin lymphoma.
  • A family history of Hodgkin lymphoma. Having a parent or sibling with Hodgkin lymphoma increases your risk of developing it.

What are the symptoms of Hodgkin lymphoma?

The signs and symptoms of Hodgkin lymphoma may include:

  • Painless, swollen lymph nodes in the neck, underarm, or groin
  • Fever for no known reason
  • Drenching night sweats (very heavy sweating during sleep)
  • Weight loss for no known reason in the past 6 months
  • Itchy skin, especially after bathing or drinking alcohol
  • Fatigue

How is Hodgkin lymphoma diagnosed?

To find out if you have Hodgkin lymphoma, your provider:

  • Will ask about your symptoms and medical history. This will include checking for signs of disease, such as lumps or anything else that seems unusual.
  • May order some lab tests, such as:
    • Complete blood count
    • Blood chemistry studies
    • Lactate dehydrogenase (LDH) test
    • Erythrocyte sedimentation rate (ESR) test
    • Blood tests to rule out other medical conditions
    • May do imaging tests such as a CT and PET (positron emission tomography) scans
    • May do a lymph node biopsy

What are the treatments for Hodgkin lymphoma?

Treatments for Hodgkin lymphoma include:

  • Chemotherapy
  • Radiation therapy
  • Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells
  • Cancer immunotherapy

Hodgkin lymphoma can usually be cured if it is found and treated early.

NIH: National Cancer Institute

Start Here

  • General Information about Adult Hodgkin Lymphoma From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Hodgkin's Lymphoma (Mayo Foundation for Medical Education and Research)
  • What Is Hodgkin Lymphoma? (American Cancer Society) Also in Spanish

Diagnosis and Tests

  • Blood Count Tests: MedlinePlus Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Bone Marrow Test From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Needle Biopsy (Mayo Foundation for Medical Education and Research) Also in Spanish
  • PDL1 (Immunotherapy) Tests From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Stages of Adult Hodgkin Lymphoma From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Stages of Childhood Hodgkin Lymphoma From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Tests for Hodgkin Lymphoma (American Cancer Society) Also in Spanish

Prevention and Risk Factors

  • Hodgkin Lymphoma Risk Factors (American Cancer Society) Also in Spanish

Treatments and Therapies

  • Bone Marrow Transplantation: MedlinePlus Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • Drugs Approved for Hodgkin Lymphoma From the National Institutes of Health (National Cancer Institute)
  • Integrative Medicine and Complementary and Alternative Therapies (Leukemia & Lymphoma Society) Also in Spanish
  • Treating Nodular Lymphocyte-Predominant Hodgkin Lymphoma (American Cancer Society) Also in Spanish
  • Treatment Option Overview (Adult Hodgkin Lymphoma) From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Treatment Option Overview (Childhood Hodgkin Lymphoma) From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Treatment Options for Primary Refractory/Recurrent Hodgkin Lymphoma in Children and Adolescents From the National Institutes of Health (National Cancer Institute) Also in Spanish

Living With

  • Living As a Hodgkin Lymphoma Survivor (American Cancer Society) Also in Spanish

Related Issues

  • General Information about AIDS-Related Lymphoma From the National Institutes of Health (National Cancer Institute) Also in Spanish
  • Hodgkin's vs. Non-Hodgkin's Lymphoma: What's the Difference? (Mayo Foundation for Medical Education and Research) Also in Spanish
  • Understanding Lymphoma and Cancer-Related Fatigue (Lymphoma Research Foundation)

Statistics and Research

  • Advances in Lymphoma Research From the National Institutes of Health (National Cancer Institute)
  • Hodgkin Lymphoma From the National Institutes of Health (National Cancer Institute)
  • Key Statistics for Hodgkin Lymphoma (American Cancer Society) Also in Spanish
  • What's New In Hodgkin Lymphoma Research? (American Cancer Society) Also in Spanish

Clinical Trials

  • ClinicalTrials.gov: Hodgkin Disease From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: Nodular Lymphocyte-Predominant Hodgkin Lymphoma: Update on Biology and Treatment.
  • Article: Newly Diagnosed Classical Hodgkin Lymphoma: Optimizing Outcomes in a New Therapeutic...
  • Article: The combination of body mass index and serum creatinine levels predicts...
  • Hodgkin Lymphoma -- see more articles

Find an Expert

  • American Cancer Society
  • Choosing a Cancer Doctor (American Cancer Society) Also in Spanish
  • Leukemia & Lymphoma Society Also in Spanish
  • Lymphoma Research Foundation
  • National Cancer Institute From the National Institutes of Health Also in Spanish
  • NCI - Designated Cancer Centers From the National Institutes of Health (National Cancer Institute) Also in Spanish

Children

  • General Information about Childhood Hodgkin Lymphoma From the National Institutes of Health (National Cancer Institute) Also in Spanish

Teenagers

  • Hodgkin Lymphoma (For Parents) (Nemours Foundation) Also in Spanish

Patient Handouts

  • Chest radiation - discharge (Medical Encyclopedia) Also in Spanish
  • Hodgkin lymphoma (Medical Encyclopedia) Also in Spanish
  • Hodgkin lymphoma in children (Medical Encyclopedia) Also in Spanish

Topic Image

Hodgkin Lymphoma

MEDICAL ENCYCLOPEDIA

  • Bone marrow biopsy
  • Chest radiation - discharge
  • Ferritin blood test
  • Hodgkin lymphoma
  • Hodgkin lymphoma in children
  • Mediastinoscopy with biopsy
  • T-cell count

Related Health Topics

  • Lymphoma

National Institutes of Health

The primary NIH organization for research on Hodgkin Lymphoma is the National Cancer Institute

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The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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