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Polycystic Ovary Syndrome
URL of this page: https://medlineplus.gov/polycysticovarysyndrome.html

Polycystic Ovary Syndrome

Also called: PCOS, Stein-Leventhal Syndrome
On this page

Basics

  • Summary
  • Start Here
  • Symptoms
  • Diagnosis and Tests
  • Treatments and Therapies

Learn More

  • Related Issues
  • Genetics

See, Play and Learn

  • No links available

Research

  • Clinical Trials
  • Journal Articles

Resources

  • Reference Desk
  • Find an Expert

For You

  • Teenagers
  • Patient Handouts

Summary

What is polycystic ovary syndrome (PCOS)?

Polycystic ovary syndrome (PCOS) is the name for set of symptoms that are related to an imbalance of hormones. PCOS affects the ovaries, as well as many other parts of the body.

People with PCOS usually have at least two of these problems:

  • Not ovulating. Normally, your ovaries make the egg that is released each month as part of a healthy menstrual cycle. This is called ovulation. But with PCOS, the egg may not develop as it should, or it may not be released during ovulation. Your periods may be irregular, or you may not have them at all.
  • High levels of androgens. Androgens are hormones that are important for normal male sexual development. Women normally make smaller amounts of androgens. Having higher levels of androgens can cause you to have extra body or facial hair (called hirsutism).
  • Cysts in one or both ovaries. Cysts are growths that are small, fluid-filled sacs.

What causes polycystic ovary syndrome (PCOS)?

The exact cause of PCOS in unknown. Research has shown that different factors may play a role, including:

  • Genetics. PCOS tends to run in families.
  • Imbalances in androgen levels.
  • Insulin resistance. This is a condition in which your body can't use insulin properly. Insulin is a hormone that helps move blood glucose (sugar) into your cells to give them energy. Insulin resistance can lead to high blood glucose levels.

What are the symptoms of polycystic ovary syndrome (PCOS)?

PCOS often develops as young as age 11 or 12, around the time of your first period. But you can develop it later.

The symptoms can vary from person to person. Some people have few or even no symptoms. They may not realize they have PCOS until they have trouble getting pregnant. Other people may have more severe symptoms.

The symptoms of PCOS may include:

  • Irregular or missed menstrual periods.
  • Too much hair on the face, chest, stomach, or thighs.
  • Obesity, weight gain, or trouble losing weight.
  • Severe acne which may be hard to treat.
  • Oily skin.
  • Patches of thickened dark skin (called acanthosis nigricans).
  • Infertility. PCOS is one of the most common causes of infertility. But many women with PCOS can still get pregnant.

What other health problems are linked to polycystic ovary syndrome (PCOS)?

PCOS is linked to many other health problems, including:

  • Insulin resistance, which can lead to prediabetes and type 2 diabetes.
  • Heart disease. Having PCOS increases your risk, and this risk goes up as you age.
  • High blood pressure.
  • High LDL ("bad") cholesterol and low HDL ("good") cholesterol. This increases your risk of heart disease.
  • Sleep apnea, a disorder that causes you to repeatedly stop breathing during sleep.
  • Depression and anxiety.

Although there are links between PCOS and these conditions, researchers do not know whether:

  • PCOS causes some of these problems
  • Some of these problems cause PCOS, or
  • There are other conditions that cause both PCOS and these other health problems

Not everyone who has PCOS will have all these problems. However, you and your health care provider may want to monitor your health for signs of them, so they can be treated early.

How is polycystic ovary syndrome (PCOS) diagnosed?

There is no specific test for PCOS. To find out if you have PCOS, your provider:

  • Will do a physical exam, which will include looking for the physical signs of PCOS.
  • Will ask about your medical history and family health history.
  • May do a pelvic exam to check for signs of extra male hormones and to see if your ovaries are enlarged or swollen.
  • May order a pelvic ultrasound to look for cysts on your ovaries and check the thickness of your endometrium (the lining of your uterus, or womb).
  • May order blood tests, including tests to check your hormone levels.

What are the treatments for polycystic ovary syndrome (PCOS)?

There is no cure for PCOS, but treatments can help you manage your symptoms. The treatments may include:

  • Lifestyle changes, which can help reduce many symptoms. They can also lower your risk for or help manage related health problems. These changes include:
    • Maintaining a healthy weight
    • Getting regular physical activity
    • Eating healthy foods
  • Medicines:
    • Hormonal birth control, such as pills, shots, and IUDs, can make your period more regular. They may also help remove acne and extra facial and body hair. But you would only use them if you don't want to get pregnant.
    • Anti-androgen medicines, which block the effect of androgens. This can help reduce hair loss on your head, the growth of facial and body hair, and acne. Providers do use them to help with these symptoms, but anti-androgen medicines are not approved by the U.S. Food and Drug Administration (FDA) to treat PCOS. These medicines can cause problems during pregnancy. Your provider may have you take them with birth control (to prevent pregnancy).
    • Insulin-sensitizing medicines, which are medicines that are used to treat type 2 diabetes. They improve insulin resistance and keep your blood glucose levels steady. They may also lower your androgen levels. They are not approved by the FDA to treat PCOS. But they may help with your symptoms.
    • Medicines for acne. These medicines come in pills, creams, or gels.
  • Treatments for hair removal, such as facial hair removal creams, laser hair removal, and electrolysis.
  • Fertility treatments if you are having trouble getting pregnant. They include medicines and procedures such as in vitro fertilization (IVF).

Start Here

  • About Polycystic Ovary Syndrome (PCOS) From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish
  • Polycystic Ovary Syndrome (Mayo Foundation for Medical Education and Research)

Symptoms

  • What Are the Symptoms of Polycystic Ovary Syndrome (PCOS)? From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Diagnosis and Tests

  • Anti-Müllerian Hormone Test From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • How Do Health Care Providers Diagnose Polycystic Ovary Syndrome (PCOS)? From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Treatments and Therapies

  • What are the treatments for PCOS? From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Related Issues

  • Diabetes and Polycystic Ovary Syndrome (PCOS) (Centers for Disease Control and Prevention) Also in Spanish
  • Hirsutism and Polycystic Ovarian Syndrome (American Society for Reproductive Medicine)
  • Treatments for Infertility Resulting from Polycystic Ovary Syndrome (PCOS) From the National Institutes of Health (Eunice Kennedy Shriver National Institute of Child Health and Human Development) Also in Spanish

Genetics

  • Polycystic ovary syndrome: MedlinePlus Genetics From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • ClinicalTrials.gov: Polycystic Ovary Syndrome From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

  • Article: Comparative study of cabergoline and hydroxychloroquine to prevent ovarian hyperstimulation syndrome...
  • Article: A Randomized Trial of Stair-Step Letrozole versus Traditional Letrozole for Subfertile...
  • Article: Flaxseed intervention and reproductive endocrine profiles in patients with polycystic ovary...
  • Polycystic Ovary Syndrome -- see more articles

Reference Desk

  • Reproductive System: Female Anatomy From the National Institutes of Health (National Cancer Institute)

Find an Expert

  • Department of Health and Human Services, Office on Women's Health Also in Spanish
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development From the National Institutes of Health Also in Spanish
  • How to Find Find an Ob-Gyn (American College of Obstetricians and Gynecologists)

Teenagers

  • PCOS: The Oral Contraceptive Pill (Boston Children's Hospital)
  • Polycystic Ovary Syndrome (Nemours Foundation)
  • Polycystic Ovary Syndrome (PCOS) in Teens: A Guide for Parents and Guardians (Boston Children's Hospital) Also in Spanish
  • Polycystic Ovary Syndrome (PCOS): General Information (Boston Children's Hospital) Also in Spanish

Patient Handouts

  • Polycystic ovary syndrome (Medical Encyclopedia) Also in Spanish

Topic Image

Polycystic Ovary Syndrome

MEDICAL ENCYCLOPEDIA

  • Polycystic ovary syndrome

Related Health Topics

  • Ovarian Cysts

National Institutes of Health

The primary NIH organization for research on Polycystic Ovary Syndrome is the Eunice Kennedy Shriver National Institute of Child Health and Human Development

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The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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